Michael Pollak Selected Research

IGF Type 1 Receptor (IGF 1 Receptor)

12/2018	Expression of IGF/insulin receptor in prostate cancer tissue and progression to lethal disease.
1/2013	Treatment with insulin analog X10 and IGF-1 increases growth of colon cancer allografts.
2/2012	The insulin and insulin-like growth factor receptor family in neoplasia: an update.
1/2012	The insulin receptor/insulin-like growth factor receptor family as a therapeutic target in oncology.
2/2011	ETV6-NTRK3-mediated breast epithelial cell transformation is blocked by targeting the IGF1R signaling pathway.
10/2009	Clinical development of inhibitors of the insulin-like growth factor receptor in oncology.
3/2009	Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma.
1/2009	Insulin receptor expression by human prostate cancers.
12/2008	Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival.
8/2008	Targeting insulin and insulin-like growth factor signalling in oncology.

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Michael Pollak Research Topics

Disease

111	Neoplasms (Cancer) 01/2022 - 07/2002
51	Breast Neoplasms (Breast Cancer) 10/2021 - 03/2002
45	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 07/2002
13	Carcinogenesis 06/2020 - 07/2005
12	Obesity 01/2022 - 01/2009
11	Inflammation (Inflammations) 10/2021 - 04/2007
10	Type 2 Diabetes Mellitus (MODY) 01/2021 - 11/2006
10	Insulin Resistance 02/2020 - 02/2004
10	Hyperinsulinism (Hyperinsulinemia) 08/2012 - 11/2006
8	Pancreatic Neoplasms (Pancreatic Cancer) 10/2017 - 12/2002
7	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 04/2004
6	Colonic Neoplasms (Colon Cancer) 01/2022 - 06/2010
4	Neoplasm Metastasis (Metastasis) 11/2020 - 10/2008
4	Ovarian Neoplasms (Ovarian Cancer) 01/2017 - 04/2007
4	Carcinoma (Carcinomatosis) 03/2016 - 09/2008
4	Hyperplasia 03/2016 - 02/2004
4	Body Weight (Weight, Body) 11/2010 - 12/2007
3	Leukemia 08/2017 - 08/2011
3	Ovarian Epithelial Carcinoma 11/2011 - 04/2007
2	Weight Loss (Weight Reduction) 02/2020 - 01/2017
2	Hepatocellular Carcinoma (Hepatoma) 08/2017 - 04/2012
2	Hypertension (High Blood Pressure) 01/2016 - 10/2008
2	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2016 - 08/2011
2	Cardiovascular Diseases (Cardiovascular Disease) 12/2014 - 12/2006
2	Diabetes Mellitus 09/2014 - 10/2008
2	Endometrial Neoplasms (Endometrial Cancer) 09/2014 - 02/2013
2	Disease Progression 09/2014 - 12/2008
2	Renal Cell Carcinoma (Grawitz Tumor) 07/2013 - 01/2013

Drug/Important Bio-Agent (IBA)

50	Insulin-Like Growth Factor I (IGF-1)IBA 01/2022 - 07/2002
44	Insulin-Like PeptidesIBA 01/2022 - 11/2002
37	Insulin (Novolin)FDA Link 01/2022 - 12/2002
30	Metformin (Glucophage)FDA LinkGeneric 01/2022 - 11/2006
24	Insulin-Like Growth Factor Binding Protein 3IBA 01/2019 - 07/2002
18	Pharmaceutical PreparationsIBA 01/2022 - 11/2006
17	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2004
16	Biomarkers (Surrogate Marker)IBA 01/2022 - 06/2005
16	Hormones (Hormone)IBA 12/2019 - 04/2007
14	Insulin-Like Growth Factor Binding ProteinsIBA 12/2019 - 07/2002
12	LeptinIBA 02/2020 - 03/2010
12	IGF Type 1 Receptor (IGF 1 Receptor)IBA 12/2018 - 12/2002
12	Insulin ReceptorIBA 12/2018 - 12/2007
11	C-PeptideIBA 01/2017 - 02/2004
10	Insulin-Like Growth Factor II (Somatomedin A)IBA 12/2019 - 04/2004
9	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 04/2008
9	Biological ProductsIBA 01/2019 - 07/2010
9	Phosphotransferases (Kinase)IBA 01/2019 - 01/2004
9	BiguanidesIBA 12/2018 - 09/2010
9	AdiponectinIBA 01/2017 - 11/2008
8	Carrier Proteins (Binding Protein)IBA 01/2022 - 02/2004
8	beta Carotene (Betacarotene)FDA Link 01/2017 - 11/2002
7	ORALIT (ORS)IBA 01/2022 - 02/2004
7	Antineoplastic Agents (Antineoplastics)IBA 01/2021 - 12/2002
7	Insulin-Like Growth Factor Binding Protein 2IBA 01/2019 - 11/2005
7	AndrogensIBA 02/2013 - 09/2007
6	Prostate-Specific Antigen (Semenogelase)IBA 01/2019 - 07/2002
6	C-Reactive ProteinIBA 04/2017 - 04/2007
6	alpha-Tocopherol FDA Link 01/2017 - 07/2003
6	SteroidsIBA 05/2012 - 08/2008
5	Interleukin-6 (Interleukin 6)IBA 01/2017 - 04/2008
5	AdipokinesIBA 01/2016 - 12/2011
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2013 - 05/2005
5	AntibodiesIBA 02/2012 - 08/2008
4	Aromatase (CYP19)IBA 03/2021 - 01/2017
4	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 10/2018 - 01/2005
4	Vitamin D FDA LinkGeneric 04/2017 - 07/2005
4	Tamoxifen FDA LinkGeneric 01/2016 - 03/2004
4	Insulin-Like Growth Factor Binding Protein 1IBA 01/2016 - 04/2008
4	BMS 536924IBA 09/2012 - 12/2008
4	Testosterone (Sustanon)FDA Link 05/2012 - 09/2011
4	Growth Hormone (Somatotropin)IBA 04/2011 - 07/2002
4	Blood Glucose (Blood Sugar)IBA 11/2010 - 11/2006
4	CarbohydratesIBA 07/2010 - 12/2007
4	Celecoxib (Celebrex)FDA Link 11/2006 - 12/2002
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 11/2020 - 04/2004
3	Serine (L-Serine)FDA Link 12/2018 - 08/2012
3	Tyrosine (L-Tyrosine)FDA Link 10/2018 - 01/2004
3	Messenger RNA (mRNA)IBA 08/2017 - 09/2007
3	Estrogens (Estrogen)FDA Link 04/2017 - 02/2013
3	EnzymesIBA 04/2017 - 04/2004
3	Tyrosine Kinase InhibitorsIBA 09/2012 - 08/2008
3	Somatomedin Receptors (Somatomedin Receptor)IBA 02/2012 - 10/2008
3	Trastuzumab (Herceptin)FDA Link 11/2006 - 12/2002
3	Growth InhibitorsIBA 11/2006 - 04/2004
2	Pregnancy-Associated Plasma Protein-A (PAPP-A)IBA 01/2022 - 01/2019
2	Phenformin (Fenformin)IBA 01/2021 - 11/2011
2	Protein Isoforms (Isoforms)IBA 01/2021 - 03/2009
2	Hypoglycemic Agents (Hypoglycemics)IBA 01/2021 - 03/2016
2	Mechanistic Target of Rapamycin Complex 1IBA 12/2018 - 08/2017
2	Insulin Glargine (Lantus)FDA Link 11/2017 - 01/2014
2	TOR Serine-Threonine KinasesIBA 08/2017 - 11/2007
2	Eukaryotic Initiation Factor-4EIBA 08/2017 - 08/2010
2	Triglycerides (Triacylglycerol)IBA 04/2017 - 01/2016
2	Octreotide (Sandostatin)FDA LinkGeneric 01/2016 - 09/2011
2	ResistinIBA 08/2014 - 01/2013

Therapy/Procedure

25	Therapeutics 01/2021 - 03/2002
8	Drug Therapy (Chemotherapy) 09/2014 - 01/2005
6	Castration 01/2019 - 11/2010
4	Mastectomy (Mammectomy) 01/2021 - 01/2016
2	Chemoprevention 02/2016 - 09/2010
2	Prostatectomy (Retropubic Prostatectomy) 12/2013 - 06/2010